Interferential therapy (IFT) is a commonly used modality in physiotherapy practice for pain relief. Pain relief is believed to be achieved through the production of endogenous opioids like endorphins and enkephalins. We report an unusual effect of interferential in which the patient reported dizziness, decreased alertness, gait disturbance and an inability to concentrate on activities of daily living such as shopping. These effects, which have been unreported in the literature to date, lasted for up to 4 h postinterferential treatment. We believe it is important for therapists to be aware of these potential side effects or excessive effects, especially with regard to specific age groups who may have premorbid balance and cognitive deficits and who are using tramadol HCl tabs. In this report, a patient with severe shoulder pain was treated with interferential currents, a commonly used modality in physiotherapy for the management of pain. He reported loss of concentration, drowsiness, decreased alertness and gait disturbance, along with analgesia, for 4–5 h after each treatment. He was regularly taking tramadol HCl for pain relief. Endogenous opioids produced in response to interferential therapy may be excessive or may interact with the tramadol HCl and potentiate its effect. There is no published report of interferential-induced symptoms, as described above, in the authors’ knowledge. The clinician using interferential currents should be aware of this possible effect.
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